Best Medicated Lip Treatments from Top Stores

Shop Nobi guide Updated October 30, 2026

Best Medicated Lip Treatments from Top Stores Medicated lip treatments on this page cost between $16 and $125.

Best Medicated Lip Treatments from Top Stores Options include serums, balms, oils and SPF-infused formulas, many featuring hyaluronic acid, peptides or antioxidants.

Best Medicated Lip Treatments from Top Stores When choosing, check for active ingredients that address your concern, hyaluronic acid for hydration, peptides for plumping, or SPF for sun protection.

Best Medicated Lip Treatments from Top Stores Texture matters: balms are richer, oils glide on, and serums absorb quickly. Look for fragrance-free options if you have sensitive lips.

U Beauty The PLASMA Lip Compound

Saint Bernard $68.00 See it at the store

No. 28 Lip Treatment Oil

Bluemercury $56.00 See it at the store

Lissant Line-Smoothing Lip Perioral Serum

Bluemercury $125.00 See it at the store

What ingredients help hydrate lips?

Hyaluronic acid, glycerin and ceramides are common hydrators in lip treatments.

Best Medicated Lip Treatments from Top Stores The full page has every pick, the whole guide and more questions. See every pick